Aminoglycosides are natural or semisynthetic antibiotics derived from actinomycetes. They were among the first antibiotics to be introduced for routine clinical use and several examples have been approved for use in humans. They found widespread use ... Aminoglycosides play a crucial role in the treatment of serious bacterial infections. 1. Classification of Aminoglycosides Aminoglycosides are a class of antibiotics that inhibit bacterial protein synthesis. The main members of this class include: Streptomycin: Streptomycin is an antibiotic medication that belongs to the class of aminoglycosides . Explore the history, structure, antimicrobial activity, mechanism of action, and overcoming resistance of aminoglycosides in this guide. Aminoglycosides - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the MSD Manuals - Medical Professional Version.