In Bombay , India, an individual was discovered to have an interesting blood type that reacted to other blood types in a way that had not been seen before. Serum from this individual contained antibodies that reacted with all RBCs from normal ABO phenotypes (i.e., groups O, A, B, and AB). Bombay Blood Group is a rare blood group first discovered in Mumbai in 1952 by Y.M. Bhende. Recently, in a rare and complex medical procedure, a 30-year-old woman with the extremely rare ‘ Bombay ’ (hh) blood group underwent a successful kidney transplant in India. When we say someone has blood group A, it means that the person has antigen of type 'A' and antibody of type 'B' in his/her blood. People with AB have both antigen A and B in their blood and no antibodies. People with O blood group have only antibodies A and B and no antigens. India achieves a medical milestone with its first cross-blood kidney transplant for a patient with the rare Bombay (hh) blood group . Learn about its significance, challenges, and breakthroughs.