Naturally occurring glucocorticoids (hydrocortisone and cortisone), which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency states. Their synthetic analogs are primarily used for their potent anti-inflammatory effects in disorders of many organ systems. It is commonly prescribed for allergic conditions such as asthma, severe allergic rhinitis, and eczema, as well as for autoimmune and inflammatory disorders like rheumatoid arthritis, systemic lupus erythematosus, and certain skin conditions. Omnacortil is a steroid medication used for inflammation and immune suppression. Learn about its uses, dosage guidelines, and important precautions. Omnacortil 40 MG Tablet can reduce your immune response and increase the risk of infection. Omnacortil 40 MG Tablet is a prescription medicine. Disperse the tablet in half a glass of water and consume. It should be taken with food to avoid stomach irritation.