Supremacy is the state of having the ultimate authority. A ruling king has supremacy over his kingdom. Supremacy means the state of being supreme or having more power than others. Learn the synonyms, pronunciation, grammar and usage of supremacy with Collins English Dictionary. Factsheet What does the noun supremacy mean? There are six meanings listed in OED's entry for the noun supremacy. See ‘Meaning & use’ for definitions, usage, and quotation evidence. Definition of supremacy noun in Oxford Advanced Learner's Dictionary. Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more.