Tottenham start their UEFA Champions League campaign at home to Villarreal on September 16. View the starting lineups and subs for the Spurs vs Villarreal match on 16.09.2025, plus access full match preview and predictions. We can confirm the starting line-ups and substitutes for our League Phase opener against Villarreal. Tottenham Hotspur vs Villarreal prediction and betting tips. Champions League preview with odds, team news and lineups. Free football predictions.