Acetazolamide is a diuretic and carbonic anhydrase inhibitor medication used to treat several illnesses. It works to cause an accumulation of carbonic acid by preventing its breakdown. FDA-approved indications include glaucoma, idiopathic intracranial hypertension, congestive heart failure, altitude sickness, periodic paralysis, and epilepsy. In addition, it is used off-label for central sleep apnea, Marfan syndrome, prevention of high-dose methotrexate nephrotoxicity, and prevention of ... Acetazolamide is a medication that is used to treat glaucoma (a condition caused by increased pressure within your eyes), oedema (abnormal buildup of fluids in the body) epilepsy (fits or convulsions) and to prevent or reduce the symptoms of mountain sickness. This medicine works by blocking the action of an enzyme called carbonic anhydrase in your body. This leads to a decrease in the production of fluid inside your eyes thereby reducing pressure within your eye. It also reduces the fluid ... Find patient medical information for Acetazolamide on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings