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Augmentin is an oral antibacterial combination consisting of amoxicillin and the beta-lactamase inhibitor, and clavulanate potassium. Learn about dosages, side effects, drug interactions, and warnings. Augmentin 625, commercially known as Augmentin 625 Duo, is an antibiotic medication used to treat a broad range of bacterial infections. This medication combines two active ingredients, amoxicillin and clavulanic acid, to work synergistically against bacteria that are often resistant to antibiotics. Amoxicillin and clavulanate potassium is a combination antibiotic used to treat bacterial infections like sinusitis, pneumonia, UTIs, ear, skin, and bronchial infections.