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Bilirubin is a yellow pigment formed from red blood cell breakdown and excreted in bile. High bilirubin levels in newborns can cause jaundice and may indicate various problems, while high bilirubin levels in adults can indicate liver or bile duct disorders. What does it mean if your Bilirubin Direct result is too high? In adults, an elevated level of direct bilirubin typically points to a blockage or disease of the liver, bile ducts, or gallbladder. This article defines bilirubin and examines the causes of elevated bilirubin levels in adults and newborns. It also looks at the symptoms and treatment options for high bilirubin levels. However, high bilirubin is usually a symptom of an underlying issue. Addressing that underlying issue is what brings your levels back down. Typical adult bilirubin levels should be below 1.2 mg/dL. Levels above this can vary from person to person and might be slightly higher in men than in women.