Blood clots can occur without any noticeable symptoms, but when symptoms do appear, they vary depending on the location of the clot, such as in the arm, leg, lungs, heart, or brain. Symptoms... Blood normally remains in its liquid state while it is within the blood vessels but when it leaves them the blood may thicken and form a gel (coagulation). Blood clotting (technically “blood coagulation”) is the process by which (liquid) blood is transformed into a solid state. A blood clot is a gel-like mass formed by platelets and fibrin in the blood to stop bleeding. Learn the types, causes, symptoms, diagnosis, treatment, complications, and prevention of blood clots. Thrombosis Thrombosis is a serious condition where one or more blood clots form in your blood vessels or heart. When this happens, the clot can block blood flow where it formed, or it can break loose and travel elsewhere in your body. If a moving clot gets stuck in a critical area, it can cause life-threatening conditions like stroke and heart attack.