Continuing Education Activity Chronic pancreatitis is a progressive inflammatory disease characterized by irreversible damage to the pancreatic tissue, destroying exocrine and endocrine functions. Over time, pancreatic parenchyma is replaced by fibrotic tissue, leading to severe abdominal pain, malabsorption, and diabetes mellitus. As the disease progresses, patients often experience debilitating symptoms and a significant decline in quality of life. The condition is linked to various causes ... Pancreatitis is a painful inflammation in your pancreas, an organ in the middle of your abdomen. It can be chronic or acute. Chronic pancreatitis is persistent inflammation of the pancreas that results in permanent structural damage with fibrosis and ductal strictures, followed by a decline in exocrine and endocrine function (pancreatic insufficiency). Heavy alcohol consumption and smoking cigarettes are two of the major risk factors. Abdominal pain is the predominant symptom in most patients. Diagnosis is usually made by imaging studies and pancreatic function testing. Treatment mainly includes pain control and ... Identify the early signs and symptoms of chronic pancreatitis to facilitate timely diagnosis and intervention. Asses patients with chronic pancreatitis for complications such as diabetes mellitus, malnutrition, and pancreatic insufficiency.