Guillain-Barré Syndrome (GBS) is a rare neurological disorder that can cause paralysis and respiratory failure. Learn about its causes, symptoms, diagnosis, and treatment options. Guillain–Barré syndrome is rare, at 1 or 2 cases per 100,000 people every year. [4][5] The syndrome is named after the French neurologists Georges Guillain and Jean Alexandre Barré, who, together with French physician André Strohl, described the condition in 1916. [7][8] Guillain-Barré syndrome (GBS) is a condition characterised by the autoimmune destruction of the peripheral sensory system[1]. It can involve sensory, motor, and autonomic nerves. There occurs temporary inflammation and demyelination of peripheral nerve myelin sheaths resulting in axonal degeneration. It is the most common cause of quickly progressive flaccid paralysis. It is believed to be one of a number of related conditions, all sharing a similar underlying autoimmune abnormality ... Guillain-Barré syndrome (GBS) is a rare condition that causes sudden numbness and muscle weakness that can affect most of your body. It happens when your immune system responds abnormally and attacks your peripheral nerves. Most people make a full recovery from GBS with treatment and rehabilitation. What is Guillain-Barré syndrome?