Hannibal is a 2001 American horror film directed by Ridley Scott from a screenplay by David Mamet and Steven Zaillian. Based on the novel of the same name by Thomas Harris, it is a sequel to the 1991 film The Silence of the Lambs. Its plot follows disgraced FBI special agent Clarice Starling as she attempts to apprehend the cannibalistic serial killer Hannibal Lecter before his surviving victim, Mason Verger, captures him. Anthony Hopkins reprises his role as Lecter, while Julianne Moore ... Criminal profiler Will Graham has a unique way of thinking that allows him to empathize with anyone, including psychopaths. While helping the FBI pursue a serial killer, he decides to enlist the brilliant psychiatrist Hannibal Lecter. Jack devises a plan to apprehend Hannibal , while Hannibal prepares for his departure. Will makes his decision, and it results in devastating consequences. Will hatches a cunning plot to slay Francis Dolarhyde, using Hannibal Lecter in his ploy. In this sequel to "The Silence of the Lambs," serial killer Hannibal Lecter's only surviving victim tries to draw him out of hiding. Watch trailers & learn more.