HLA-B27 stands for Human leukocyte antigen B27 . It is a protein found on the surface of our white blood cells (WBCs) and it is a blood test that identifies HLA-B27 proteins. Although most human leukocyte antigens (HLAs) protect your body from harm, HLA-B27 is a specific type of protein that contributes to immune system dysfunction. An HLA-B27 presence can result in an autoimmune disease or immune-mediated disease, like juvenile rheumatoid arthritis or ankylosing spondylitis. Fig. Collecting ... The HLA B27 test explicitly measures the presence or absence of the HLA B27 gene variant in an individual's DNA. The test focuses on identifying the specific genetic sequence associated with the HLA B27 gene. The first human leukocyte antigen ( HLA ) haplotype association with inflammatory disease was discovered in 1972, correlating HLA-B27 with ankylosing spondylitis. This remains one of the strongest known associations of disease with HLA-B27 . HLA-B27 is an antigen and the test for this is also known by names, such as histocompatibility leukocyte A antigen; human leukocyte A antigen and Human Lymphocyte Antigen B27 . If you are HLA-B27 positive , then it means that you are at increased risk than others for some autoimmune conditions like reactive arthritis and ankylosing spondylitis.(1, […]
