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Known for its "grape-like" clusters due to swollen hydropic villi, hydatidiform moles are categorized into 2 types: complete and partial. A complete mole arises when an empty egg is fertilized by 1 or 2 sperm, resulting in a genome with only paternal DNA. Learn about the definition, epidemiology, etiology, diagnosis and treatment of complete hydatidiform mole, a gestational trophoblastic disease with villous hydrops and trophoblastic hyperplasia. See ultrasound, histologic and molecular images and references. A hydatidiform mole (molar pregnancy) is a gestational trophoblastic disease. Ultrasonography is used to identify both complete and partial molar pregnancies. (See the image below.) Treatment consists of evacuation of the uterus by dilation and curettage. Gestational Trophoblastic Diseases: Part 1: Complete and Partial Hydatidiform Moles What are gestational trophoblastic diseases? Gestational trophoblastic diseases (GTDs) are a spectrum of tumors and tumor-like conditions characterized by the abnormal proliferation of placental tissue. This proliferation can involve the villous or trophoblastic components of the placenta. GTDs are heterogeneous in presentation, both clinically and histopathologically, and are commonly associated with a ...