Ill definition: of unsound physical or mental health; unwell; sick.. See examples of ILL used in a sentence. Get a fresh look at ILL in this unsettling new trailer for the upcoming first-person action/horror game from developer Team Clout in collaboration with Mundf... In the U.S. the two words are used practically interchangeably except that sick is always used when the word modifies the following noun: He looks sick (ill); a sick person. The meaning of ILL is not in good health; also : nauseated. How to use ill in a sentence.

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