Kaposi sarcoma: Is a cancerous tumor associated with a

Kaposi sarcoma is a cancerous tumor associated with a virus that typically appears on the skin and around the mouth, nose, genitals, or anus. Kaposi sarcoma (KS) is an indolent angio-proliferative spindle-cell tumor derived from endothelial and immune cells infected with human herpes virus type 8 (HHV-8; also known as Kaposi sarcoma herpes virus [KSHV]). HHV-8 is identified as the causative agent of KS; it is present in 95-98% of all cases. [1] KS is categorized into the following 4 types [2] : Kaposi's sarcoma (KS) is a type of cancer that can form masses on the skin, in lymph nodes, in the mouth, or in other organs. [4][6] The skin lesions are usually painless, purple, and may be flat or raised. [6][8] Lesions can occur singly, multiply in a limited area, or may be widespread. [6] . Classic Kaposi sarcoma (CKS) is a rare vascular disease mainly found in populations of Mediterranean origin. The pathogenesis involves Human Herpes Virus 8 (HHV8) and genetic mutations such as SNP309 in the MDM2 gene.