Synonyms for LARGE : sizable, substantial, considerable, big, huge, handsome, great, oversized; Antonyms of LARGE : small, smallish, little, puny, dwarf, dinky, undersized, tiny Definition of Large in the Definitions.net dictionary. Meaning of Large . What does Large mean? Information and translations of Large in the most comprehensive dictionary definitions resource on the web. Both " Large " and "Big" are adjectives used to describe size or magnitude. " Large " is commonly used in more formal contexts or when detailing measurements. For instance, clothing sizes like " large " or "extra- large " indicate a specific set of measurements. Learn the meaning, synonyms, and idioms of the adjective large , which means having a relatively great size, quantity, extent, etc. Compare and contrast with big and great, and see examples of large in different contexts.