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Seeing low lymphocytes on a blood test can be stressful, but it’s important to understand what they mean. Learn when to worry about low lymphocytes . Lymphopenia is having a lower-than-normal level of lymphocytes in your blood. You may or may not need treatment depending on what causes your low lymphocyte levels. Low lymphocyte count means your lymphocyte count is less than 1000 cells per microliter of blood. Know the major causes and proper treatments. And, when should you see a doctor if routine bloodwork reveals you have extremely high or low levels of lymphocytes ? Read on for the answers to these and other questions.