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Levocetirizine+Montelukast is a combination medication used to treat allergy sy mptoms like sneezing, runny nose, itchy eyes, and cough. It works by blocking two different chemicals in the body that trigger allergic reactions. Levocetirizine blocks histamine, which causes many allergy symptoms, while Montelukast blocks leukotrienes, which contribute to inflammation in the airways. This combination helps reduce allergy symptoms effectively. The combination of montelukast with levocetirizine gives additional benefits in comparison to either drug alone and could be considered for patients whose quality of life is impaired by persistent allergic rhinitis. Methodology: The tablet was prepared having immediate release layer of levocetrizine and sustained release layer of Montelukast. Discover the uses of Montelukast Sodium and Levocetirizine Hydrochloride Tablet for allergy relief and asthma management. Learn about precautions and side effects for patients. Compare Levocetirizine vs Montelukast head-to-head with other drugs for uses, ratings, cost, side effects and interactions.