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Piperacillin and tazobactam for injection, USP is supplied as a white to yellowish powder in vials of the following sizes: Each piperacillin and tazobactam for injection, USP 2.25 g vial provides ... Piperacillin and Tazobactam package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology. Learn about the uses, side effects, precautions, and dosage of piperacillin and tazobactam injection, a combination of penicillin and beta-lactamase inhibitor antibiotics. This medication is used to treat certain bacterial infections, but it may interact with hormonal contraceptives and cause diarrhea. Tazobactam is a beta-lactamase inhibitor that reduces resistance and enhances the activity of Piperacillin against bacteria. Tazomac 4.5gm Injection can be used to treat many different bacterial infections such as ear, sinus, throat, lung, urinary tract, skin, teeth, joints, and bones.