Tazobactam is a beta-lactamase inhibitor that reduces resistance and enhances the activity of Piperacillin against bacteria. Pipzo 4.5 g Injection can be used to treat many different bacterial infections such as ear, sinus, throat, lung, urinary tract, skin, teeth, joints, and bones. Piperacillin and tazobactam combination injection is used to treat bacterial infections in many different parts of the body (eg, stomach or bowel, lungs, skin, female reproductive organs). Piperacillin + Tazobactum is used in the treatment of Bacterial infections. View Piperacillin + Tazobactum’s uses, side-effects, drug interactions, expert advice and user FAQs only on 1mg.com. Piperacillin and tazobactam injection is used to treat pneumonia and skin, gynecological, and abdominal (stomach area) infections caused by bacteria. Piperacillin is in a class of medications called penicillin antibiotics.