5 meanings : 1. a period of isolation or detention, esp of persons or animals arriving from abroad, to prevent the spread of.... Click for more definitions. Quarantine definition : a strict isolation imposed to prevent the spread of disease.. See examples of QUARANTINE used in a sentence. Definition of quarantine noun in Oxford Advanced Learner's Dictionary. Meaning , pronunciation, picture, example sentences, grammar, usage notes, synonyms and more. quarantine meaning , definition , what is quarantine : a period of time when a person or animal...: Learn more.

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