Sciatica is a sensation in which you feel a moderate to intense pain in your back, buttocks, and legs. Learn about the cause and treatment. SCIATICA definition: 1. pain in the lower part of the back and the back of the legs 2. pain in the lower part of the…. Learn more. Sciatica is a set of symptoms caused by irritation or compression of the sciatic nerve, which runs from the lower back to the legs. Learn about the causes, symptoms, diagnosis, and treatment options for sciatica, and how to prevent it. Sciatica is a serious condition that results from pressure on the sciatic nerve, the largest nerve in the human body, formed by the union of 5 nerves from the lower part of the spine. The most common cause of sciatica is related to discs like disc herniation or bony overgrowths.

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