Structure of skin: Learn about the three layers

Learn about the three layers of the skin: epidermis, dermis, and hypodermis. Find out their structure, composition, functions, and variations across the body. The skin is the largest organ in the body, covering its entire external surface. The skin has 3 layers—the epidermis, dermis, and hypodermis, which have different anatomical structures and functions (see Image. Cross Section, Layers of the Skin). Layers of the Skin Although you may not typically think of the skin as an organ, it is in fact made of tissues that work together as a single structure to perform unique and critical functions. The skin and its accessory structures make up the integumentary system, which provides the body with overall protection. The skin is made of multiple layers of cells and tissues, which are held to underlying structures by connective tissue (Figure 1). The deeper layer of skin is well vascularized (has ... You have three main skin layers—epidermis, dermis, and hypodermis (subcutaneous tissue). Each performs a specific function to protect you and keep you healthy.