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Master synthesis in chemistry-discover key factors, top examples & real-life applications. Start learning now with Vedantu! SYNTHESIS definition: 1. the production of a substance from simpler materials after a chemical reaction 2. the mixing of…. Learn more. Synthesis is the process or result of combining separate elements or substances to form a coherent whole. It can also refer to reasoning from the general to the particular, or to the formation of a chemical compound from simpler compounds or elements. The noun 'synthesis' has its etymology rooted in Greek. It is derived from the Greek word 'sunthesis,' which combines 'sun,' meaning 'together,' and 'thesis,' meaning 'a placing' or 'a proposition.' In Greek, 'sunthesis' referred to the act of placing different things together to form a whole or the composition of various elements into a unified entity. 'Synthesis' entered the English language in the 17th century and is used to describe the process of combining different elements or ...