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Oct 14, 2022 ·Depressionis a mood disorder that causes a persistent feeling of sadness and loss of interest. Also called major depressive disorder or clinicaldepression, it affects how you feel, think and behave and can lead to a variety of emotional and physical problems. Depressionis a whole-body illness. It involves the body, mood, and thoughts.Depressionaffects the way you eat and sleep. It also can affect the way you feel about yourself and things. It is not the same as being unhappy or in a “blue” mood. It is not a sign of personal weakness or a condition that can be willed or wished away. When you havedepression, you can’t “pull yourself ... Depression(also called majordepression, major depressive disorder, or clinicaldepression) is different. It can cause severe symptoms that affect how a person feels, thinks, and handles daily activities, such as sleeping, eating, or working.Depressioncan affect anyone regardless of age, sex, race or ethnicity, income, culture, or education. Information aboutdepressionincluding the different types ofdepression, signs and symptoms, diagnosis, treatment options, and how to find help.